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How ampullary cancer can affect your health?

Cancer of the ampulla of Vater is rare cancer that begins in the digestive tract area called the ampulla of Vater. The ampulla of Vater is where the bile and pancreatic ducts meet and are excreted into the small intestine.

Primary piece cancer occurs near many other parts of the digestive tract, such as the liver, pancreas, and small intestine. As the tumor grows, this can affect other organs.



The most common symptom of this cancer is jaundice. This is yellowing of the skin and eyes. This happens because a tumor in the ampulla of Vater blocks the bile duct. When bile flow is blocked from entering the intestines, it enters the blood and causes yellowing of the skin.

Other symptoms of cancer are:

Decreased appetite

Weight loss

stomach ache

Back pain

Itchy skin

Stomach upset and vomiting

Many of these symptoms can be caused by other health problems. Your healthcare provider will do tests and special tests to find out if you have cancer.


Treatment options for giant cancer include:

  • Surgery to remove the pancreas and small intestine. Whipple surgery (pancreaticoduodenectomy) eliminates the head of the pancreas, part of the small intestine (duodenum), gallbladder, and part of the bile duct.
  • Whipple surgery can be performed as a minimally invasive surgery using a large incision in the abdomen or using several small incisions.
  • Minimally invasive surgery. For tiny, large tumors or precancerous tumors, an instrument through an endoscope can remove cancer (endoscopic surgery). This may be an option in some cases.
  • Combination of chemotherapy and radiation therapy. Chemotherapy uses drugs to kill cancer cells. Radiation therapy uses energy beams such as x-rays and protons to kill cancer cells. When these treatments are used together, they may be more effective against many cancers.
It is an extremely rare type of cancer. It begins as a malignant tumor in the part of the body called the ampulla of vater,  which is located where the bile duct meets the small intestine. You can read more about it on
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